Nitric Oxide
Nitric oxide is an endothelium-derived pulmonary arterial vasodilator.
NO has a wide variety of physiological roles, but clinically sees application only as a pulmonary vasodilator.
Indications
Two broad use-cases exist:
- RV failure and pulmonary hypertension
- Hypoxia
Ideally ↑ V/Q matching by reversing pulmonary constriction in ventilated alveoli.
Contraindications
Anatomy
Equipment
Technique
Complications
- B
- Methaemoglobinaemia
<5% acceptable. - Lung toxicity
- NO2
Should be monitored.
- NO2
- Methaemoglobinaemia