Platelets

Platelets testing includes:

Abnormalities

Thrombocytopaenia
- Causes include:
  - Artifactual
    Clumping of platelets in an inadequately anticoagulated tube.
  - ↑ Consumption
    - Extracorporeal circulation
    - DIC
    - Haemorrhage
    - Post-transfusion
    - Pre-eclampsia
    - MAHA
      - TTP/HUS
    - Immune
      - HITT
      - APS
      - SLE
  - ↓ Production
    - Drugs
      - Alcohol
      - Linezolid = * Bone marrow disease
      - Myelofibrosis
      - Aplastic anaemia
    - Malignancy
      - Bone marrow infiltration
      - Haematological malignancy
    - Infection
      - Viral
        HIV, EBV, Hepatitis C, mumps, rubella, VZV.
    - Nutritional deficiency
  - Sequestration
    - Hypersplenism
    - Hypothermia